H-Tyr-Phe-OH (L-Tyrosyl-L-phenylalanine) 是一种具有口服活性的ACE抑制剂,50 μM 的抑制率为 48%。H-Tyr-Phe-OH 可作为生物标记,用于区分良性甲状腺结节 (BTN) 和甲状腺癌 (TC)。H-Tyr-Phe-OH 具有黄嘌呤氧化酶抑制 (降尿酸) 活性,可做为中性粒细胞样细胞中 IL-8 产生的调节剂。
产品描述
H-Tyr-Phe-OH (L-Tyrosyl-L-phenylalanine) is an orally active inhibitor of Angiotensin converting enzyme ( ACE ), with an inhibiton rate of 48% at 50 μM. H-Tyr-Phe-OH can be used as an biomarker for differentiating benign thyroid nodules (BTN) from thyroid cancer (TC). H-Tyr-Phe-OH exhibits xanthine oxidase inhibition (uric acid lowering) activity and serves as regulator in IL-8 production in neutrophil-like cells [1] [2] [3] [4].
Cas No.
17355-11-2
分子式
C18H20N2O4
分子量
328.36
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years