ATX inhibitor 16 是一种有效的ATX抑制剂,IC50为 0.0021 μM。ATX inhibitor 16 在乳腺癌细胞中显示出优异的抗增殖活性。
产品描述
ATX inhibitor 16 is a potent ATX inhibitor with an IC 50 of 0.0021 μM. ATX inhibitor 16 shows excellent anti-proliferative activities in breast cancer cells [1].
体外活性
ATX inhibitor 16 (compound 9j) (0-15 μM; 72 h) shows excellent anti-proliferative activities in breast cancer cells [1]. Cell Cytotoxicity Assay [1] Cell Line: MCF7, MDA-MB-231, A549, H2228 cells Concentration: 0-15 μM Incubation Time: 72 h Result: Exhibited excellent anti-proliferative activities with IC 50 s of 0.43, 0.31, 10.98, 7.18 μM for MCF7, MDA-MB-231, A549, H2228 cells, respectively.
Cas No.
2484811-36-9
分子式
C28H27F3N6OS2
分子量
584.68
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years