产品描述
PDE5-IN-2 is a potent, highly selective, and orally active inhibitor of PDE5(IC50 of 0.31 nM)
体外活性
PDE5-IN-2 has at least 1000-fold selectivity over PDE1B, PDE3A, PDE7A1, PDE8A1, and PDE9A2 (IC50s, >32 000 nM)[1].
体内活性
PDE5-IN-2 shows anti-pulmonary arterial hypertension activity[1].
Cas No.
2244517-61-9
分子式
C25H21N3O6S
分子量
491.52
别名
PDE5-IN-2
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years