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17R(18S)-EpETE
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
17R(18S)-EpETE图片
CAS NO:725246-18-4
包装:1 mg
市场价:-1元

产品介绍

产品描述

17R(18S)-EpETE is an oxylipin and a cytochrome P450 metabolite of eicosapentaenoic acid .1,217R(18S)-EpETE is an activator of large-conductance calcium-activated potassium (BKCa) channels, increasing the potassium current amplitude by 15-fold in isolated rat cerebral artery vascular smooth muscle cells (VSMCs) at +60 mV when used at a concentration of 50 nM.2It has negative chronotropic effects in isolated neonatal rat cardiomyocytes (NRCMs; EC50= ~1-2 nM) and prevents calcium-induced increases in the spontaneous beating of NRCMs.3,4

Cas No.

725246-18-4

分子式

C20H30O3

分子量

318.45

别名

17R(18S)-EpETE

储存和溶解度

Ethanol:Soluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years