产品描述
Pepstatin Ammonium is a specific inhibitor of aspartic proteaseproduced by actinomycetes(hemoglobin-pepsin, hemoglobin-proctase, casein-pepsin, casein-proctase, casein-acid protease and hemoglobin-acid protease with IC50s of 4.5 nM, 6.2 nM, 150 nM, 290 nM, 520 nM and 260 nM , respectively). Pepstatin Ammonium also inhibits HIV protease.
体外活性
Pepstatin inhibits the recombinant HIV protease with an IC50 of 250 μM.
体内活性
Pepstatin suppresses stomach ulceration of the pylorus in ligated Shay rats[1].
Cas No.
T12407
分子式
C34H66N6O9
分子量
702.92
别名
Pepstatin A Ammonium;Pepstatin Ammonium
储存和溶解度
DMSO:41.67 mg/mL (59.28 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years