LTA4H-IN-1 是一种有效的白三烯 A4 水解酶LTA4H抑制剂，IC50值为 2 nM，可用于炎症和自身免疫性疾病研究。

LTA4H-IN-1 is a potent inhibitor of leukotriene A4 hydrolase (LTA4H) with an IC 50 of 2 nM. LTA4H-IN-1 can be used for the research of inflammatory and autoimmune disorders [1].

LTA4H-IN-1 (15 min) inhibits the LTA4H-catalyzed hydrolysis of 7-amino-4-methylcoumarin (AMC) derivative of Arginine (Arg-AMC) with an IC 50 of 2 nM [1]. LTA4H-IN-1 (30 min) inhibits LTB4 biosynthesis in a human whole blood assay (hWB), with an IC 50 of 167 nM [1].

LTA4H-IN-1 (0.3 mg/kg; a single p.o.) inhibits the -43% release of LTB4 compared to vehicle control in mice [1].

1799681-85-8

C16H14ClFN6O3

392.77

LTA4H-IN-1

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years