Algestone acetophenide 是用于发情同步的孕酮,已被评估为与庚酸雌二醇联合使用的注射避孕药。它在治疗上也用作局部抗炎药,并在治疗痤疮时局部应用。
产品描述
Algestone acetophenide is progesterone that used in estrus synchronization and has been evaluated as an injectable contraceptive in combination with estradiol enanthate. It is also used therapeutically as a topical anti-inflammatory and is applied topically in the therapy of ACNE.
体外活性
Every 21 days or so, each female received a single dose of combined hormonal contraceptive (algestone acetophenide and 17-enanthate estradiol) in a total of five doses throughout the experiment.?The physiological parameters were accessed by means of 13 blood samples from each female, whereas three were gathered during the baseline and 10 samples were collected during the treatment phase.?The results showed that the contraceptive use provoked changes in hematological coagulation factors such as an increase in the amount of platelets (p = 0.039) and a reduction in both prothrombin (p0.001) and thromboplastin coagulation time (p0.001).?These results are similar to what has been observed in human patients[1].
Cas No.
24356-94-3
分子式
C29H36O4
分子量
448.59
别名
Neolutin;苯甲孕酮;Algestone acetophenide
储存和溶解度
DMSO:10.83 mg/ml (24.15 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years