您好,欢迎来到试剂信息网! [登录] [免费注册]
试剂信息网
位置:首页 > 产品库 > Adapalene sodium salt
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Adapalene sodium salt
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Adapalene sodium salt图片
CAS NO:911110-93-5
包装:5 mg
市场价:9850元

产品名称
阿达帕林钠
CD 271 sodium salt
产品介绍

产品描述

Adapalene (CD 271; Differin) sodium salt is a synthetic retinoid and a Retinoic acid receptor agonist.

体外活性

Adapalene sodium salt is a third-generation topical retinoid primarily used in the treatment of mild-moderate acne and is also used (off-label) to treat keratosis pilaris as well as other skin conditions. Adapalene sodium salt is possibly more effective than tretinoin 0.025% gel in the treatment of acne vulgaris [1].

体内活性

Thirty-six rats of either sex were divided into six groups (two control groups, and an etodolac, indomethacin, tretinoin, and adapalene sodium salt group) of six animals each. Each group was given different drugs or chemicals. The inhibitory activities of the drugs were determined on carrageenan-induced rat paw oedema. The inhibition rate (53.48%) in the tretinoin group was found to be higher than the adapalene sodium salt and controls (P< 0.05). Adapalene sodium salt was found to have an inhibition rate of 10.28%, and when compared with the other groups, it was found to have no statistically significant anti-inflammatory activity [2].

Cas No.

911110-93-5

分子式

C28H28NaO3

分子量

435.51

别名

阿达帕林钠;CD 271 sodium salt;Adapalene sodium salt

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years