IDO1/TDO-IN-1 (30) 是IDO1(非竞争性, Ki为 0.23 μM) andTDO(竞争性, Ki为 0.73 μM) 的双抑制剂。IDO1/TDO-IN-1 (30) 通过潜在的线粒体介导的BCL-2/Bax通路显著促进细胞凋亡。

IDO1/TDO-IN-1 (30) is a potent dual IDO1 (uncompetitive, K i of 0.23 μM) and TDO (competitive, K i of 0.73 μM) inhibitor. IDO1/TDO-IN-1 (30) significantly promotes cell apoptosis through the potential mitochondria-mediated Bcl-2/Bax pathway [1].

2379527-72-5

C21H16O6

364.35

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years