IDO1/2-IN-1 hydrochloride 是第一个有效的IDO1/IDO2双重抑制剂,对 IDO1 和 IDO2 的IC50分别为 28 nM 和 144 nM。IDO1/2-IN-1 hydrochloride 具有抗肿瘤活性。具有口服活性。
产品描述
IDO1/2-IN-1 hydrochloride (compound 4t) is the first potent IDO1/IDO2 dual inhibitor with IC 50 s of 28 nM and 144 nM for IDO1 and IDO2, respectively. IDO1/2-IN-1 hydrochloride exhibits antitumor activies. Orally active [1].
Cas No.
2310286-60-1
分子式
C16H19BrClFN8O4
分子量
521.73
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years