产品描述
Estrogen receptor antagonist 2 is used for the study of breast cancer.Estrogen receptor antagonist 2 is a potent and orally active estrogen receptor (ER) antagonist.
体内活性
Estrogen receptor antagonist 2 (oral administration;?0.8-40 mg/kg;?30 days) decreases tumor growth as a dose-dependent manner.?It gives almost complete tumour growth inhibition at the doses >10 mg/kg in mice.Estrogen receptor antagonist 2 (oral administration;?0.2-50 mg/kg;?20 days) exhibits anti-tumour efficacy as a dose-dependent manner in human parental MCF7 mice xenograft.
Cas No.
2222844-89-3
分子式
C24H28F4N6
分子量
476.51
别名
Estrogen receptor antagonist 2;Camizestrant
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years