PDHK-IN-4 (Compound 30) 是一种有效的PDHK抑制剂，对 PDHK2 和 PDHK4 的IC50s 分别为 0.0051 和 0.0122 μM。丙酮酸脱氢酶激酶 (PDHK) 是许多疾病（包括糖尿病和癌症）的迷人药物靶点。PDHK-IN-4 具有研究癌症疾病的潜力。

PDHK-IN-4 (Compound 30) is a potent inhibitor of PDHK with IC 50 s of 0.0051 and 0.0122 μM for PDHK2 and PDHK4, repectively. Pyruvate dehydrogenase kinases (PDHKs) are fascinating drug targets for numerous diseases, including diabetes and cancers. PDHK-IN-4 has the potential for the research of cancer diseases [1].

C24H25N5O3

431.49

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years