Dehydronitrosonisoldipine是一种不育α和含TIR图案1的抑制剂,可用于有关神经退行性疾病的研究。Dehydronitrosonisoldipine抑制轴突退化和长春碱激活的神经元中cADPR的产生。
产品描述
Dehydronitrosonisoldipine is an inhibitor of sterile α and TIR motif-containing 1 and can be used in studies about neurodegenerative disorders. Dehydronitrosonisoldipine inhibits axon degenration and the Vincristine-activated cADPR production in neurons.
体外活性
Dehydronitrosonisoldipine exhibits an IC50 of 4 μM in the sterile α and TIR motif-containing 1-dN-expression cells, and decreases the cellular cADPR[1].
Cas No.
87375-91-5
分子式
C20H22N2O5
分子量
370.4
别名
Dehydronitrosonisoldipine
储存和溶解度
DMSO:100 mg/mL (269.98 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years