Herquline A is an alkaloid fungal metabolite originally isolated from P. herquei. It inhibits cell death induced by influenza A strain A/PR/8/34 in MDCK cells with an IC50 value of 10 μg/ml and inhibits viral replication in a plaque assay in a concentration-dependent manner. Herquline A also inhibits platelet aggregation induced by ADP and platelet-activating factor (PAF) in vitro (IC50s = 180 and 240 μM, respectively).

71812-08-3

C19H26N2O2

314.42

Herquline A

DMSO:Soluble
Methanol:Soluble
Ethanol:Soluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years