KBU2046 是口服有效的，体外细胞运动和侵袭的高选择性抑制剂。它结合伴侣异源复合物，选择性地改变调节运动性的侣伴蛋白的结合，并且缺乏经典HSP90抑制剂的所有标志。它抑制癌症转移并延长寿命。

KBU2046 is an oral inhibitor of cell motility and cell invasion in vitro. KBU2046 inhibits cancer metastasis and prolongs life. KBU2046 binds chaperone heterocomplexes, selectively alters binding of client proteins that regulate motility, and lacks all of the hallmarks of classical HSP90 inhibitors.

1143863-69-7

C15H11FO2

242.25

KBU2046

DMSO:50 mg/mL (206.40 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years