MC-Val-Cit-PAB 是一种组织蛋白酶可裂解的 ADC 接头，用于制备抗体-药物偶联物。

MC-Val-Cit-PAB is a cathepsin cleavable ADC linker that is used for making antibody-drug conjugate. FDA approved drugs such as brentuximab vedotin use this linker.

159857-80-4

C28H40N6O7

572.663

N-[6-(2,5-二氢-2,5-二氧代-1H-吡咯-1-基)-1-氧代己基]-L-缬氨酰-N5-(氨基甲酰基)-N-[4-(羟甲基)苯基]-L-鸟氨酰胺;MC-Val-Cit-PAB

DMSO:22 mg/mL (38.42 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years