产品描述
BRD5631 is an autophagy enhancer through an mTOR-independent pathway. It affects several cellular disease phenotypes linked to autophagy, including cell survival, protein aggregation, and inflammatory cytokine production.
体外活性
BRD5631 (10 μM, 48 hours) leads to increased levels of LC3-II in HeLa cells. BRD5631 stimulates the formation of new autophagosomes. BRD5631 suppressed IL-1β secretion in an autophagy-dependent manner. BRD5631 does not enhance autophagy by directly inhibiting mTOR or the mTOR signaling pathway.
Cas No.
2446154-91-0
分子式
C30H35N3O4
分子量
501.62
别名
BRD5631
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years