LRRK2-IN-3 (化合物 24) 是一种有效,选择性,具有口服活性和可透过血脑屏障的LRRK2抑制剂,在 hPBMCs 中的IC50值为 0.6 nM。LRRK2-IN-3 可用于帕金森氏病的研究。
产品描述
LRRK2-IN-3 (compoubd 24) is a potent, selective, orally active and brain-penetrant inhibitor LRRK2, with IC 50 of 2.6 nM in human PBMCs. LRRK2-IN-3 can be used for the research of Parkinson's disease [1].
Cas No.
2641054-60-4
分子式
C25H29ClF2N6O2
分子量
518.99
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years