Methylatropine is an antagonist of muscarinic acetylcholine receptors (IC50=<0.1 nM in a radioligand binding assay using isolated porcine brain membranes) and a derivative of atropine .1,2It reduces acetylcholine-induced decreases in blood pressure in rats when administered intravenously with an ED50value of 5.5 μg/kg.2Methylatropine reduces salivation, induces mydriasis, and increases heart rate in dogs.3

52-88-0

C18H26N2O6

366.41

Methylatropine (nitrate)

DMSO:30 mg/mL
DMF:30 mg/mL
Ethanol:30 mg/mL
PBS (pH 7.2):10 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years