Methyl 5-hydroxypyridine-2-carboxylate 是存在于Mahonia fortune茎中的一种酚酸,在体外表现出 NO 抑制活性。
产品描述
Methyl 5-hydroxypyridine-2-carboxylate is a phenolic acid found in the stems of Mahonia fortune. Methyl 5-hydroxypyridine-2-carboxylate exhibits NO inhibitory effects in vitro.
体外活性
Methyl 5-hydroxypyridine-2-carboxylate (compound 2) inhibits NO in LPS-stimulated RAW264.7 and BV2 cells, with IC 50 s of 115.67 and 118.80 μM, respectively [1]. Methyl 5-hydroxypyridine-2-carboxylate (6.25-200μM) does not have any cytotoxic effect [1].
Cas No.
30766-12-2
分子式
C7H7NO3
分子量
153.14
别名
Methyl 5-hydroxypyridine-2-carboxylate
储存和溶解度
DMSO:50 mg/mL (326.50 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years