EBOV-GP-IN-1 (Compound 28) 是一种有效的Ebola进入抑制剂,对埃博拉病毒包膜糖蛋白(EBOV-GP)的IC50为 0.05 μM。
产品描述
EBOV-GP-IN-1 (Compound 28) is a potent Ebola entry inhibitor with an IC 50 of 0.05 μM against Ebola virus envelope glycoprotein ( EBOV-GP ) [1].
体外活性
EBOV-GP-IN-1 (Compound 28) (0-80 μM, 2 days) shows cytotoxicity with a CC 50 of 5.10 ± 1.56 μM for Huh7 cells in pseudotyped virus assay [1]. EBOV-GP-IN-1 exhibits remarkable selectivity between EBOV-GP and VSV-G (vesicular stomatitis virus glycoprotein) (Spec. Index = 58) [1].
分子式
C25H40ClN3O2
分子量
450.06
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years