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Oxantel Pamoate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Oxantel Pamoate图片
CAS NO:68813-55-8
包装与价格:
包装价格(元)
100 mg电议
200 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
酚嘧啶扑蛲灵
Oxantel embonate
产品介绍
Oxantel pamOATe 是驱虫剂,有效针对Trichuris muris和钩虫。

产品描述

Oxantel pamoate is used as an Antinematodal agent.

体内活性

The activity of the veterinary drug Oxantel pamoate is studied against Trichuris muris, Ancylostoma ceylanicum and Necator americanus. An ED50s of 4.7 mg/kg is calculated for Oxantel pamoate against T. muris in mice. Combinations of Oxantel pamoate with pyrantel pamoate behaved antagonistically (combination index (CI)=2.53). Oxantel pamoate combined with Levamisole, Albendazole or Ivermectin using ratios based on their ED50s reveals antagonistic effects (CI=1.27, 1.90 and 1.27, respectively). A highly synergistic effect (CI=0.15) is observed when Oxantel pamoate-mebendazole is administered to T. muris-infected mice. Oxantel pamoate (10 mg/kg) lacks activity against Ancylostoma ceylanicum and Necator americanus[1].

Cas No.

68813-55-8

分子式

C36H32N2O7

分子量

604.659

别名

酚嘧啶扑蛲灵;Oxantel embonate;Oxantel Pamoate

储存和溶解度

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years