Liothyronine sodium hydrate 是一种有效的甲状腺激素。Liothyronine sodium hydrate 是有效的TRα和TRβ激动剂,对 hTRα 和 hTRβ 的Ki值均为 2.33 nM。
产品描述
Liothyronine sodium hydrate is an active form of thyroid hormone. Liothyronine sodium hydrate is a potent thyroid hormone receptors TRα and TRβ agonist with K i s of 2.33 nM for hTRα and hTRβ, respectively [1] [2] [3].
体外活性
Liothyronine (T3, 100 nM) sodium hydrate stimulates the proliferation of hepatocarcinema cells in which TRβ1 is overexpressed [1]. Liothyronine sodium hydrate binds to human β1 thyroid hormone receptor (hTRβ1), and changes its conformation. Liothyronine sodium hydrate promotes growth, induces differentiation and regualtes metabolic effects [2].
Cas No.
345957-19-9
分子式
C15H13I3NNaO5
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years