7-BIA is a receptor-type protein tyrosine phosphatase D (PTPRD) inhibitor (IC50: 1-3 μM).

7-BIA inhibits recombinant human PTPRD and recombinant human PTPRS (IC50s: ~1–3 μM and 40 μM).

7-BIA (10-20 mg/kg; given i.p.; only once) reduces cocaine self-administration in highly experienced WT mice.

Animal Model: WT mice (available cocaine 50 times, 1 mg/kg infusions on FR1 schedule during ≥20 prior sessions). Dosage: 10 mg/kg, 20 mg/kg. Administration: Given i.p.; only once

1313403-49-4

C15H18O6

294.3

7-BIA

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years