2-Phthalimidehydroxy-acetic acid 是一种属于 ALKyl chain 类的 PROTAC linker,可用于 PROTAC 分子的合成。
产品描述
2-Phthalimidehydroxy-acetic acid is an alkyl chain-based PROTAC linker that can be used in PROTAC synthesis.
体外活性
PROTACs contain two different ligands connected by a linker; one of them is a ligand for an E3 ubiquitin ligase and the other one is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Cas No.
134724-87-1
分子式
C10H7NO5
分子量
221.17
别名
2-Phthalimidehydroxy-acetic acid
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years