KYA1797 is an inhibitor of the Wnt/?-CATenin pathway. KYA1797 binds directly to the regulators of G-protein signaling domain of axin, initiats ?-CATenin and Ras degradation through enhancement of the ?-CATenin destruction complex activating GSK3?, effectively suppresses the growth of CRCs harboring APC and KRas mutations.

KYA1797 is an inhibitor of the Wnt/ss-catenin pathway. KYA1797 binds directly to the regulators of G-protein signaling domain of axin, initiats ss-catenin and Ras degradation through enhancement of the ss-catenin destruction complex activating GSK3ss, effectively suppresses the growth of CRCs harboring APC and KRAS mutations.

851304-36-4

C17H12N2O6S2

404.42

KYA1797

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years