FXIa-IN-6 是一种有效的FXIa抑制剂，对大多数相关丝氨酸蛋白酶具有选择性（Ki= 0.3 nM）。FXIa-IN-6 还在多个临床前物种中展示了出色的药代动力学 (PK) 特性（高口服生物利用度和低清除率）。

FXIa-IN-6 is a potent FXIa inhibitor with selectivity against most of the relevant serine proteases ( K i = 0.3 nM). FXIa-IN-6 also demonstrated excellent pharmacokinetics (PK) profile (high oral bioavailability and low clearance) in multiple preclinical species.

1551460-43-5

C31H29ClF2N4O4

595.04

FXIa-IN-6

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years