(S,R,S)-AHPC-C10-NH2 包含基于 (S,R,S)-AHPC 的VHL配体和 1 个 linker，是一种合成的 E3 连接酶配体-linker 偶联物 (E3 ligase ligand-linker conjugate)。用于 BET 的靶向 PROTAC 的合成。

(S,R,S)-AHPC-C10-NH2 is a synthesized E3 ligase ligand-linker conjugate incorporating the (S,R,S)-AHPC based VHL ligand and a linker used for BET-Targeted PROTAC.

PROTACs contain two different ligands connected by a linker; one of them is a ligand for an E3 ubiquitin ligase and the other one is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2].

2341796-74-3

C33H51N5O4S

613.85

VH032-C10-NH2;(S,R,S)-AHPC-C10-NH2

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years