sRANKL-IN-1 (compound S3) 是sRANKL(soluble RANKL) 的抑制剂。sRANKL-IN-1 对破骨细胞具有较强的抑制作用，IC50值为 0.096 μM，KD值为 34.80 μM。sRANKL-IN-1 可用于骨质疏松症的研究。

sRANKL-IN-1 (compound S3) is a sRANKL (soluble RANKL) inhibitor. sRANKL-IN-1 shows a potent osteoclast inhibition effect with an IC 50 value of 0.096 μM and a KD value of 34.80 μM. sRANKL-IN-1 can be used for the research of osteoporosis [1].

sRANKL-IN-1 (0-50 μM) shows potent inhibition to osteoclast [1]. Cell Viability Assay [1] Cell Line: Bone marrow cell line Concentration: 0-50 μM Incubation Time: Until osteoclasts formed Result: Inhibited osteoclasts formation with an IC 50 value of 0.096 μM and a KD value of 34.80 μM.

331968-10-6

C18H18N4O6S

418.42

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years