AuRORa/LIM 激酶-IN-1 (Compound F114) 是一种有效的auRORa和lim激酶的双重抑制剂。AuRORa 激酶和 lim 激酶分别参与肿瘤细胞分裂和细胞运动。AuRORa/LIM 激酶-IN-1 抑制 GBM 增殖和侵袭。AuRORa/LIM 激酶-IN-1 是一种很有前途的新型 AuRORa/lim 激酶双抑制剂支架，可用于未来 GBM 和潜在其他癌症的药物开发工作。

Aurora/LIM kinase-IN-1 (Compound F114) is a potent and dual inhibitor of aurora and lim kinase. Aurora kinases and lim kinases are involved in neoplastic cell division and cell motility, respectively. Aurora/LIM kinase-IN-1 inhibits GBM proliferation and invasion. Aurora/LIM kinase-IN-1 is a promising new scaffold for dual aurora/lim kinase inhibitors that may be used in future drug development efforts for GBM, and potentially other cancers [1].

C16H20N6O

312.37

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years