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T-91825
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
T-91825图片
CAS NO:189345-04-8
包装与价格:
包装价格(元)
5 mg电议
10 mg电议

产品介绍

产品描述

T-91825 (PPI-0903M), an N-phosphono-type cephalosporin, is the active form of TAK-599. T-91825 is active against both gram-positive and gram-negative bacteria[1][2].

体外活性

PPI-0903M is very active against S. aureus (MIC50=0.25 μg/mL), including methicillin-resistant (MRSA) strains (MIC50=1 μg/mL)[1].PPI-0903M is active against hetero-vancomycin-intermediate S. aureus (100 strains), with MIC50s ranging from 0.25 to 4 μg/mL[1].

体内活性

AK-599 (20 mg/kg; s.c. three times a day for 2 days) decreases the bacterial cell counts in lungs more than 99.9% in a mouse pneumonia model caused by MRSA[2].

Cas No.

189345-04-8

分子式

C22H20N8O5S4

分子量

604.71

别名

T-91825

储存和溶解度

DMSO:100 mg/mL (165.37 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years