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AT2 receptor agonist C21
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
AT2 receptor agonist C21图片
CAS NO:477775-14-7
包装:100 mg
市场价:8517元

产品介绍

产品描述

AT2 receptor agonist C21 is a druglike selective agonist of angiotensin II AT2 receptor(Ki of 0.4 nM and >10 μM for the AT2 receptor and AT1 receptor, respectively).

体内活性

AT2 receptor agonist C21, with a bioavailability of 20-30% after oral administration and a half-life estimated to 4 h in rat. Which induces outgrowth of neurite cells, stimulates p42/p44mapk, enhances in vivo duodenal alkaline secretion in Sprague-Dawley rats. And it lowers the mean arterial blood pressure in anesthetized, spontaneously hypertensive rats[1].

Cas No.

477775-14-7

分子式

C23H29N3O4S2

分子量

475.62

别名

AT2 receptor agonist C21

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years