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Beta-Zearalanol
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Beta-Zearalanol图片
CAS NO:42422-68-4
包装:25 mg
市场价:10471元

产品介绍

产品描述

Beta-Zearalenol is the derivative of zearalenone (ZEA) which can conjugate with glucuronic acid[2] and it is an mycotoxin produced by Fusarium spp, which causes apoptosis and oxidative stress in mammalian reproductive cells[1].

体外活性

βeta-Zearalenol (0-200 μM; 24 hours) inhibits BGC proliferation in a dose-dependent manner, with an IC50 of 25 μM[1]. βeta-Zearalenol (0-10 μM; 72 hours) has the highest inhibition effect on the all three investigated cytokines: IL-8, IL-1β and TNF-α by comparation with ZEA or α-Zearalenol[2]. βeta-Zearalenol (0-100 μM; 72 hours) shows high toxic with an IC50 of 15.2 μM in the HepG2 cells, synergistic effect of β-ZOL+ZEN or β-ZOL+α-ZOL with IC50 values of 19.8 uM, 16.8 uM, respectively[2].

Cas No.

42422-68-4

分子式

C18H26O5

分子量

322.4

别名

Beta-Zearalanol

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years