Nrf2 activator-4 (Compound 20a) 是一种高效的、具有口服活性的Nrf2激活剂，EC50值为 0.63 μM。Nrf2 activator-4 抑制小神经胶质细胞中活性氧 (Reactive Oxygen Species) 的产生。Nrf2 activator-4 在 scopolamine 诱导的小鼠模型中能有效地恢复学习和记忆损伤。

Nrf2 activator-4 (Compound 20a) is a highly potent, orally active Nrf2 activator with an EC 50 of 0.63 μM. Nrf2 activator-4 suppresses reactive oxygen species against oxidative stress in microglia. Nrf2 activator-4 effectively recovers the learning and memory impairment in a scopolamine-induced mouse model [1].

2383016-68-8

C23H24ClF3N2O3

468.9

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years