Cyclopentolate Hydrochloride 是一种阿托品样毒蕈碱受体拮抗剂,是眼科常用的抗毒蕈碱剂,对睫状肌毒蕈碱受体的 pKB值为 7.8。
产品描述
Cyclopentolate Hydrochloride is a muscarinic acetylcholine receptors antagonist with Kis of 1.62, 27.5, and 2.63 nM for M1, M2, and M3 receptors, respectively.
体外活性
Cyclopentolate Hydrochloride inhibits carbachol-induced contraction of isolated human iris sphincter, circular ciliary muscle, and longitudinal ciliary muscle (Kbs = 7.9, 15.8, and 12.5 nM, respectively[1].
Cas No.
5870-29-1
分子式
C17H26ClNO3
分子量
327.85
别名
Cyclopentolate Hydrochloride
储存和溶解度
DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years