Glutaric acid 是一种 C5 二羧酸，是色氨酸和赖氨酸分解代谢途径中的中间体。Glutaric acid 影响周细胞的收缩性和迁移。Glutaric acid 是 I 型戊二酸尿症的生物指标。

Glutaric acid is a simple five-carbon linear dicarboxylic acid. Glutaric acid is naturally produced in the body during the metabolism of some amino acids, including lysine and tryptophan

Glutaric acid (1 and 2 mM) is able to reduce TRAP measurement by up to 28% in a dose-dependent manner (β=0.77; P<0.001). Furthermore, a significantly inverse correlation is also verified between chemiluminescence and TRAP (β=0.81; P<0.001). Glutaric acid does not alter the activities of Cat and SOD, but strongly inhibits (up to 46%) the activity of GPx even at the lower concentration used (0.5 mM). It is observed that the metabolite inhibits this activity in a dose-dependent manner at concentrations as low as 0.05 mM[2].

110-94-1

C5H8O4

132.11

Glutaric acid

DMSO:10 mM
H2O:5 mg/mL
Ethanol:Soluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years