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Glutaric acid
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Glutaric acid图片
CAS NO:110-94-1
包装与价格:
包装价格(元)
100 mg电议
1 mL*10 mM(in DMSO)电议

产品介绍
Glutaric acid 是一种 C5 二羧酸,是色氨酸和赖氨酸分解代谢途径中的中间体。Glutaric acid 影响周细胞的收缩性和迁移。Glutaric acid 是 I 型戊二酸尿症的生物指标。

产品描述

Glutaric acid is a simple five-carbon linear dicarboxylic acid. Glutaric acid is naturally produced in the body during the metabolism of some amino acids, including lysine and tryptophan

体外活性

Glutaric acid (1 and 2 mM) is able to reduce TRAP measurement by up to 28% in a dose-dependent manner (β=0.77; P<0.001). Furthermore, a significantly inverse correlation is also verified between chemiluminescence and TRAP (β=0.81; P<0.001). Glutaric acid does not alter the activities of Cat and SOD, but strongly inhibits (up to 46%) the activity of GPx even at the lower concentration used (0.5 mM). It is observed that the metabolite inhibits this activity in a dose-dependent manner at concentrations as low as 0.05 mM[2].

Cas No.

110-94-1

分子式

C5H8O4

分子量

132.11

别名

Glutaric acid

储存和溶解度

DMSO:10 mM
H2O:5 mg/mL
Ethanol:Soluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years