Endothelin 1 acts through two types of receptors ETA and ETB. Endothelin 1 (swine, human) is a synthetic peptide with the sequence of human and swine Endothelin 1, which is a potent endogenous vasoconstrictor.

It acts through two types of receptors: ETA and ETB.?Apart from a vasoconstrictive action, ET-1 causes fibrosis of the vascular cells and stimulates production of reactive oxygen species.?It is claimed that ET-1 induces proinflammatory mechanisms, increasing superoxide anion production and cytokine secretion.Endothelin-1 (ET-1) is a potent endogenous vasoconstrictor, mainly secreted by endothelial cells.

117399-94-7

C109H159N25O32S5

2491.9

Endothelin 1 (swine, human)

H2O:50 mg/mL (20.07 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years