(2R,4R)-APDC is a specific group II metabotropic glutamate receptors (mGluRs) agonist. (2R,4R)-APDC has anticonvulsant and neuroprotective effects. References: [1]. Folbergrová J, et al. Posttreatment with group II metabotropic glutamate receptor agonist 2R,4R-4-aminopyrrolidine-2,4-dicarboxylate is only weakly effective on seizures in immature rats. Brain Res. 2009 Jun 1;1273:144-54.
[2]. Yao H, et al. 2R, 4R-APDC decreases cell proliferation in the dentate gyrus of adult rats: the effect of 2R, 4R-APDC on cell proliferation. Neuroreport. 2007 Sep 17;18(14):1459-62.
纯度:≥98%
CAS:169209-63-6