Polyketomycin is a tetracyclic quinone glycoside antibiotic isolated from Streptomyces sp. or Streptomyces diastatochromogenes. Polyketomycin inhibits growth of Gram-positive bacteria, and its MIC values is less than 0.2 μg/mL. Polyketomycin has antibacterial, anticancer, antimalarial activities. References: [1]. Momose I, et al. Polyketomycin, a new antibiotic from Streptomyces sp. MK277-AF1. I. Taxonomy, production, isolation, physico-chemical properties and biological activities. J Antibiot (Tokyo). 1998 Jan;51(1):21-5. [2]. Daum M, et al. Organisation of the biosynthetic gene cluster and tailoring enzymes in the biosynthesis of the tetracyclic quinone glycoside antibiotic polyketomycin. Chembiochem. 2009 Apr 17;10(6):1073-83. [3]. Otoguro K, In vitro antimalarial activities of the microbial metabolites. J Antibiot (Tokyo). 2003 Mar;56(3):322-4.

纯度：≥98%

CAS：200625-47-4