ILS-920 is a nonimmunosuppressive Rapamycin analog with reduced immunosuppressive activity and highly potent neuroprotective activity. ILS-920 binds specificly to the immunophilin FKBP52 and to the β1-subunit of L-type voltage-gated calcium channels (VGCC). ILS-920 shows 200-fold selectivity for FKBP52 versus FKBP12. References: [1]. Ruan B, et al. Binding of rapamycin analogs to calcium channels and FKBP52 contributes to their neuroprotective activities. Proc Natl Acad Sci U S A. 2008 Jan 8;105(1):33-8.

纯度：≥98%

CAS：892494-07-4