IC50: 0.19 μM (α4β4); 0.37 μM (α4β2); 0.41 μM (α3β2); 1.3 μM (α2β2); 2.3 μM (α2β4); 23.1 μM (α3β4) References: [1]. Harvey SC, et al. Multiple determinants of dihydro-beta-erythroidine sensitivity on rat neuronal nicotinic receptor alpha subunits. J Neurochem. 1996 Nov;67(5):1953-9.
[2]. Tabbara RI, et al. Nicotine enhances responding for conditioned reinforcement via α4β2 nicotinic acetylcholine receptors in the ventral tegmental area, but not the nucleus accumbens or the prefrontal cortex. Neuropharmacology. 2019 Apr;148:68-76.
[3]. Clementson S, et al. Enantioselective Total Synthesis of (+)-Dihydro-β-erythroidine. J Am Chem Soc. 2019 Jun 5;141(22):8783-8786.
纯度:≥98%
CAS:29734-68-7