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Brexpiprazole
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Brexpiprazole图片
CAS NO:913611-97-9
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议

产品名称
OPC 34712, OPC-34712
产品介绍

生物活性

Brexpiprazole是一种新型的D2多巴胺部分激动剂研究产品,目前正在临床试验中,用于治疗抑郁症,精神分裂症和注意缺陷多动障碍(ADHD)。

靶点信息

5-HT1Ahuman noradrenergic α1BDopamine D2L5-HT2A receptorsα2C receptors
0.12 nM(Ki)0.17 nM(Ki)0.3 nM(Ki)0.47 nM(Ki)0.59 nM(Ki)

化学数据

目录号A13527
作用机制Agonist (激动剂)
M. Wt433.5733
FormulaC25H27N3O2S
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.913611-97-9
SynonymsOPC 34712, OPC-34712
SMILESC1CN(CCN1CCCCOC2=CC3=C(C=C2)C=CC(=O)N3)C4=C5C=CSC5=CC=C4

溶解度

In vitroDMSO21 mg/mL (48.43 mM)
WaterInsoluble
EthanolInsoluble
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM23.06 mL115.32 mL230.64 mL
0.5 mM4.61 mL23.06 mL46.13 mL
1 mM2.31 mL11.53 mL23.06 mL
5 mM0.46 mL2.31 mL4.61 mL

*The above data is based on the productmolecular weight 433.5733. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.