RP-001 HCl is a picomolar short-acting S1P1 (EDG1) specific agonist, with an EC50 of 9 pM. RP-00 HCl induces internalization and polyubiquitination of S1P1. RP-001 HCl has little activity on S1P2-S1P4 and only moderate affinity for S1P5. References: [1]. Cahalan SM, et al. Actions of a picomolar short-acting S1P1 agonist in S1P1-eGFP knock-in mice. Nat Chem Biol. 2011 May;7(5):254-6.

纯度：≥98%

CAS：1781880-34-9