BOS172722 is a novel, potent and selective inhibitor of monopolar spindle 1 (MPS1) with IC50 of 2-11 nM. BOS172722 showed high bioavailability in all three species despite very modest solubility at physiological pH. MPS1 occupies a central role in mitosis and is one of the main components of the spindle assembly checkpoint. The MPS1 kinase is an attractive cancer target.

纯度：≥98%

CAS：1578245-44-9