T-1105 (T1105), an analog of T-705 (favipiravir), is a novel and potent broad-spectrum antiviral inhibitor that inhibits the polymerases of RNA viruses after being converted to the actiive form: ribonucleoside triphosphate (RTP) metabolite. T-1105 has a broad spectrum of antiviral activity against various RNA viruses, including Zika virus (ZIKV), influenza virus, arenaviruses, bunyaviruses, West Nile virus (WNV), yellow fever virus (YFV), and foot-and-mouth disease virus (FMDV).