Description: T-705RTP sodium, the sodium salt of T-705RTP, is the triphosphoralated active metabolite of T-705, which is a novel and potent influenza virus RNA polymerase inhibitor that has activity against RNA viruses. As a selective and GTP-competitive influenza virus RNA polymerase inhibitor, it exhibits IC50 of 0.14 μM and a Ki of 1.52 μM.

References:

[1]. Furuta Y, et al. Mechanism of action of T-705 against influenza virus. Antimicrob Agents Chemother. 2005 Mar;49(3):981-6.

[2]. Sangawa H, et al. Mechanism of action of T-705 ribosyl triphosphate against influenza virus RNA polymerase. Antimicrob Agents Chemother. 2013 Nov;57(11):5202-8.

纯度：≥98%

CAS：356783-10-3