N-Acetyl-Calicheamicin (N-Acetyl-Calicheamicin γ; N-Acetyl-γ-calicheamicin), the N-acetylated analog of calicheamicin, is a novel and potent antitumor antibiotic of the enediyne class. It could be used as a potential warhead (cytotoxic DNA-binding agent) in antibody-drug-conjugation (ADC). Calicheamicins are naturally occurring hydrophobic enediyne antibiotics found in the actinomycete Micromonospora echinospora calichensis. Calicheamicins act by binding to DNA in the minor groove, and causing strand scission.

纯度：≥98%

CAS：108212-76-6