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Ixazomib citrate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Ixazomib citrate图片
CAS NO:1239908-20-3
规格:≥98%
包装与价格:
包装价格(元)
50mg电议
100mg电议
250mg电议
500mg电议
1g电议

产品介绍

Ixazomib citrate (MLN9708; MLN-9708; MLN 9708), the citrate salt and orally bioavailable prodrug of Ixazomib (MMLN2238; MMLN-2238), is a selective inhibitor of 20S proteasome (IC50 = 3.4 nM) with potential anticancer activity. It is being studies in a Phase II trial to treat multiple myeloma, amyloidosis and lymphoma in sorts of countries. Ixazomib citrate is a boron-containing compound that has to be hydrolyzed to MLN2238 (ixazomib) which is pharmacologically active. Compared with bortezomib, MLN9708 has improved pharmacokinetics, pharmacodynamics, and antitumor activity in preclinical studies.

纯度:≥98%

CAS:1239908-20-3