CM4620 (CM-4620) is a novel, potent and selective calcium-release activated calcium-channel (CRAC) inhibitor with antiinflammatory effects. CM-4620 acts as a selective inhibitor of the calcium channel ORAI1 and is being researched for the treatment of pancreatitis. It inhibits Orai1/STIM1 and Orai2/STIM1 channels with IC50s of 119, 895 nM, respectively.
纯度:≥98%
CAS:1713240-67-5