AZ1 is a novel and potent dual inhibitor of the USP25/28 deubiquitinating enzyme subfamily with potential anticancer activity. It has been reported that Ubiquitin specific proteases (USPs) are linked to critical axes for therapeutic intervention and USP28 is required for c-Myc stability, suggesting that
USP28 inhibition may represent a novel approach to targeting this so far
undruggable oncogene.
纯度:≥98%
CAS:2165322-94-9